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KURISAWA, Motoichi Adviser to the President, Professor
Materials Science, Materials Chemistry Frontiers, Research Center for Exponential Biomedical DX (Excellent Core)

Published Papers

90 items
Self-Assembled Daunorubicin/Epigallocatechin Gallate Nanocomplex for Synergistic Reversal of Chemoresistance in Leukemia.
Ki Hyun Bae, Fritz Lai, Betul Oruc, Motomi Osato, Qingfeng Chen, Motoichi Kurisawa
International journal of molecular sciences, 24, 1, -, 2022
Bone marrow-targetable Green Tea Catechin-Based Micellar Nanocomplex for synergistic therapy of Acute myeloid leukemia.
Ki Hyun Bae, Fritz Lai, Jamie Mong, Akiko Niibori-Nambu, Kiat Hwa Chan, Zhisheng Her, Motomi Osato, Min-Han Tan, Qingfeng Chen, Motoichi Kurisawa
Journal of nanobiotechnology, 20, 1, 481-481, 2022
An Injectable Multifunctional Dual-Phase Bead-Reinforced Gelatin Matrix Permissive of Mesenchymal Stem Cell Infiltration for Musculoskeletal Soft Tissue Repair.
Dajiang Du, Zhen Liu, Wanting Niu, Ding Weng, Teck Chuan Lim, Motoichi Kurisawa, Myron Spector
Advanced healthcare materials, 10, 18, e2100626-, 2021
Integrating biomaterials and food biopolymers for cultured meat production
Shengyong Ng, Motoichi Kurisawa
Acta Biomaterialia, 124, 108-129, 2021
Platelet-Derived Growth Factor Stimulated Migration of Bone Marrow Mesenchymal Stem Cells into an Injectable Gelatin-Hydroxyphenyl Propionic Acid Matrix.
Wanting Niu, Teck Chuan Lim, Abdulmonem Alshihri, Ravikumar Rajappa, Lishan Wang, Motoichi Kurisawa, Myron Spector
Biomedicines, 9, 2, -, 2021
Hyaluronic acid–green tea catechin conjugates as a potential therapeutic agent for rheumatoid arthritis
Fan Lee, Ki Hyun Bae, Shengyong Ng, Atsushi Yamashita, Motoichi Kurisawa
RSC Advances, -, 2021
Injectable gelatin hydroxyphenyl propionic acid hydrogel protects human retinal progenitor cells (hRPCs) from shear stress applied during small-bore needle injection
Colombe Dromel, P., Singh, D., Alexander-Katz, A., Kurisawa, M., Spector, M., Young, M.
Applied Materials Today, 19, -, 2020
Hydrogel-Based Therapy for Brain Repair After Intracerebral Hemorrhage
Lim, T.C., Mandeville, E., Weng, D., Wang, L.-S., Kurisawa, M., Leite-Morris, K., Selim, M.H., Lo, E.H., Spector, M.
Translational Stroke Research, 11, 3, 412-417, 2020
The effects of shock wave stimulation of mesenchymal stem cells on proliferation, migration, and differentiation in an injectable gelatin matrix for osteogenic regeneration
Alshihri, A., Niu, W., Kämmerer, P.W., Al-Askar, M., Yamashita, A., Kurisawa, M., Spector, M.
Journal of Tissue Engineering and Regenerative Medicine, 14, 11, 1630-1640, 2020
A two-pronged anti-leukemic agent based on a hyaluronic acid–green tea catechin conjugate for inducing targeted cell death and terminal differentiation
Kun Liang, Ki Hyun Bae, Akiko Nambu, Bibek Dutta, Joo Eun Chung, Motomi Osato, Motoichi Kurisawa
Biomaterials Science, 8, 1, 497-505, 2020
Hyaluronic acid hydrogels with defined crosslink density for the efficient enrichment of breast cancer stem cells
Susi Tan, Atsushi Yamashita, Shu Jun Gao, Motoichi Kurisawa
Acta Biomaterialia, 94, 320-329, 2019
Carrier-Enhanced Anticancer Efficacy of Sunitinib-Loaded Green Tea-Based Micellar Nanocomplex beyond Tumor-Targeted Delivery
Nunnarpas Yongvongsoontorn, Joo Eun Chung, Shu Jun Gao, Ki Hyun Bae, Atsushi Yamashita, Min-Han Tan, Jackie Y. Ying, Motoichi Kurisawa
ACS Nano, 13, 7, 7591-7602, 2019
Mechanically and chemically defined hydrogel matrices for patient-derived colorectal tumor organoid culture
Ng, S., Tan, W.J., Pek, M.M.X., Tan, M.-H., Kurisawa, M.
Biomaterials, 219, 119400-119400, 2019
In Situ Cross-linking Hydrogel as a Vehicle for Retinal Progenitor Cell Transplantation
Park, J., Baranov, P., Aydin, A., Abdelgawad, H., Singh, D., Niu, W., Kurisawa, M., Spector, M., Young, M.J.
Cell Transplantation, 28, 5, 596-606, 2019
Promoting Neuro-Supportive Properties of Astrocytes with Epidermal Growth Factor Hydrogels
Chan, S.J., Niu, W., Hayakawa, K., Hamanaka, G., Wang, X., Cheah, P.S., Guo, S., Yu, Z., Arai, K., Selim, M.H., Kurisawa, M., Spector, M., Lo, E.H.
Stem Cells Translational Medicine, 8, 12, 1242-1248, 2019
Recent advances in the design of injectable hydrogels for stem cell-based therapy
Kun Liang, Ki Hyun Bae, Motoichi Kurisawa
Journal of Materials Chemistry B, 7, 24, -, 2019
Peroxidase-immobilized porous silica particles for in situ formation of peroxidase-free hydrogels with attenuated immune responses
Li, L., Bae, K.H., Ng, S., Yamashita, A., Kurisawa, M.
Acta Biomaterialia, 81, 103-114, 2018
Highly Augmented Drug Loading and Stability of Micellar Nanocomplexes Composed of Doxorubicin and Poly(ethylene glycol)–Green Tea Catechin Conjugate for Cancer Therapy
Liang, K., Chung, J.E., Gao, S.J., Yongvongsoontorn, N., Kurisawa, M.
Advanced Materials, 30, 14, e1706963-, 2018
Hyaluronic acid-green tea catechin micellar nanocomplexes: Fail-safe cisplatin nanomedicine for the treatment of ovarian cancer without off-target toxicity
Bae, K.H., Tan, S., Yamashita, A., Ang, W.X., Gao, S.J., Wang, S., Chung, J.E., Kurisawa, M.
Biomaterials, 148, -, 2017
Emerging hydrogel designs for controlled protein delivery
Bae, K.H., Kurisawa, M.
Biomaterials Science, 4, 8, -, 2016
Growth inhibitory effect of an injectable hyaluronic acid-tyramine hydrogels incorporating human natural interferon-α and sorafenib on renal cell carcinoma cells
Ueda, K., Akiba, J., Ogasawara, S., Todoroki, K., Nakayama, M., Sumi, A., Kusano, H., Sanada, S., Suekane, S., Xu, K., Bae, K.H., Kurisawa, M., Igawa, T., Yano, H.
Acta Biomaterialia, 29, 103-111, 2016
Targeted intracellular protein delivery based on hyaluronic acid-green tea catechin nanogels
Liang, K., Ng, S., Lee, F., Lim, J., Chung, J.E., Lee, S.S., Kurisawa, M.
Acta Biomaterialia, 33, -, 2016
Self-assembled ternary complexes stabilized with hyaluronic acid-green tea catechin conjugates for targeted gene delivery
Liang, K., Bae, K.H., Lee, F., Xu, K., Chung, J.E., Gao, S.J., Kurisawa, M.
Journal of Controlled Release, 226, -, 2016
Liposomal delivery of horseradish peroxidase for thermally triggered injectable hyaluronic acid-tyramine hydrogel scaffolds
Ren, C.D., Kurisawa, M., Chung, J.E., Ying, J.Y.
Journal of Materials Chemistry B, 3, 23, -, 2015
Microstructured dextran hydrogels for burst-free sustained release of PEGylated protein drugs
Bae, K.H., Lee, F., Xu, K., Keng, C.T., Tan, S.Y., Tan, Y.J., Chen, Q., Kurisawa, M.
Biomaterials, 63, -, 2015
Synthesis and bioactivity of a conjugate composed of green tea catechins and hyaluronic acid
Lee, F., Lim, J., Reithofer, M.R., Lee, S.S., Chung, J.E., Hauser, C.A.E., Kurisawa, M.
Polymer Chemistry, 6, 24, -, 2015
Enzyme-mediated hyaluronic acid-tyramine hydrogels for the propagation of human embryonic stem cells in 3D
Xu, K., Narayanan, K., Lee, F., Bae, K.H., Gao, S., Kurisawa, M.
Acta Biomaterialia, 24, -, 2015
Injectable hydrogel systems crosslinked by horseradish peroxidase
Lee, F., Bae, K.H., Kurisawa, M.
Biomedical Materials (Bristol), 11, 1, -, 2015
Hyaluronidase-incorporated hyaluronic acid-tyramine hydrogels for the sustained release of trastuzumab
Xu, K., Lee, F., Gao, S., Tan, M.-H., Kurisawa, M.
Journal of Controlled Release, 216, -, 2015
Cartilage synthesis in hyaluronic acid-tyramine constructs
Ren, C.D., Gao, S., Kurisawa, M., Ying, J.Y.
Journal of Materials Chemistry B, 3, 9, -, 2015
Enzymatic conjugation of a bioactive peptide into an injectable hyaluronic acid-tyramine hydrogel system to promote the formation of functional vasculature
Wang, L.-S., Lee, F., Lim, J., Du, C., Wan, A.C.A., Lee, S.S., Kurisawa, M.
Acta Biomaterialia, 10, 6, -, 2014
Self-assembled micellar nanocomplexes comprising green tea catechin derivatives and protein drugs for cancer therapy
Chung, J.E., Tan, S., Gao, S.J., Yongvongsoontorn, N., Kim, S.H., Lee, J.H., Choi, H.S., Yano, H., Zhuo, L., Kurisawa, M., Ying, J.Y.
Nature Nanotechnology, 9, 11, -, 2014
Oxidation as a facile strategy to reduce the surface charge and toxicity of polyethyleneimine gene carriers
Seow, W.Y., Liang, K., Kurisawa, M., Hauser, C.A.E.
Biomacromolecules, 14, 7, -, 2013
Injectable hyaluronic acid-tyramine hydrogels incorporating interferon-α2a for liver cancer therapy
Xu, K., Lee, F., Gao, S.J., Chung, J.E., Yano, H., Kurisawa, M.
Journal of Controlled Release, 166, 3, -, 2013
Injectable biodegradable hydrogels: Progress and challenges
Bae, K.H., Wang, L.-S., Kurisawa, M.
Journal of Materials Chemistry B, 1, 40, -, 2013
Chemotactic recruitment of adult neural progenitor cells into multifunctional hydrogels providing sustained SDF-1α release and compatible structural support
Lim, T.C., Rokkappanavar, S., Toh, W.S., Wang, L.-S., Kurisawa, M., Spector, M.
FASEB Journal, 27, 3, -, 2013
Modulation of mesenchymal stem cell chondrogenesis in a tunable hyaluronic acid hydrogel microenvironment
Toh, W.S., Lim, T.C., Kurisawa, M., Spector, M.
Biomaterials, 33, 15, -, 2012
Controlling fibroblast proliferation with dimensionality-specific response by stiffness of injectable gelatin hydrogels
Wang, L.-S., Chung, J.E., Kurisawa, M.
Journal of Biomaterials Science, Polymer Edition, 23, 14, -, 2012
Hydrodynamic spinning of hydrogel fibers
Hu, M., Deng, R., Schumacher, K.M., Kurisawa, M., Ye, H., Purnamawati, K., Ying, J.Y.
Biomaterials, 31, 5, 863-869, 2010
The development of a nanocrystalline apatite reinforced crosslinked hyaluronic acid-tyramine composite as an injectable bone cement
Shona Pek, Y., Kurisawa, M., Gao, S., Chung, J.E., Ying, J.Y.
Biomaterials, 30, 5, -, 2009
Cell immobilization in gelatin-hydroxyphenylpropionic acid hydrogel fibers
Hu, M., Kurisawa, M., Deng, R., Teo, C.-M., Schumacher, A., Thong, Y.-X., Wang, L., Schumacher, K.M., Ying, J.Y.
Biomaterials, 30, 21, 3523-3531, 2009
An injectable hyaluronic acid-tyramine hydrogel system for protein delivery
Lee, F., Chung, J.E., Kurisawa, M.
Journal of Controlled Release, 134, 3, -, 2009
Enzymatic synthesis of a catechin conjugate of polyhedral oligomeric silsesquioxane and evaluation of its antioxidant activity
Ihara, N., Kurisawa, M., Chung, J.E., Uyama, H., Kobayashi, S.
Applied Microbiology and Biotechnology, 66, 4, -, 2005
Injectable biodegradable hydrogels composed of hyaluronic acid-tyramine conjugates for drug delivery and tissue engineering
Kurisawa, M., Chung, J.E., Yang, Y.Y., Gao, S.J., Uyama, H.
Chemical Communications, 34, 34, 4312-4314, 2005
PH dependence of polypseudorotaxane formation between cationic linear polyethylenimine and cyclodextrins
Choi, H.S., Ooya, T., Lee, S.C., Sasaki, S., Kurisawa, M., Uyama, H., Yui, N.
Macromolecules, 37, 18, 6705-6710, 2004
Oxidative coupling of epigallocatechin gallate amplifies antioxidant activity and inhibits xanthine oxidase activity
Kurisawa, M., Chung, J.E., Uyama, H., Kobayashi, S.
Chemical Communications, 4, 3, -, 2004
Spontaneous change of physical state from hydrogels to crystalline precipitates during poly-pseudorotaxane formation
Choi, H.S., Ooya, T., Sasaki, S., Yui, N., Kurisawa, M., Uyama, H., Kobayashi, S.
ChemPhysChem, 5, 9, -, 2004
Amplification of antioxidant activity of catechin by polycondensation with acetaldehyde
Chung, J.E., Kurisawa, M., Kim, Y.-J., Uyama, H., Kobayashi, S.
Biomacromolecules, 5, 1, -, 2004
Amplification of inhibitory activity of catechin against disease-related enzymes by conjugation on poly(ε-lysine)
Ihara, N., Schmitz, S., Kurisawa, M., Chung, J.E., Uyama, H., Kobayashi, S.
Biomacromolecules, 5, 5, -, 2004
New tyrosinase inhibitors, (+)-catechin-aldehyde polycondensates
Kim, Y.-J., Chung, J.E., Kurisawa, M., Uyama, H., Kobayashi, S.
Biomacromolecules, 5, 2, -, 2004
Effects of polyrotaxane structure on polyion complexation with DNA
Ooya, T., Yamashita, A., Kurisawa, M., Sugaya, Y., Maruyama, A., Yui, N.
Science and Technology of Advanced Materials, 5, 3, -, 2004
Thermoresponsive hydrogels based on biodegradable poly(amino acid)s
Tachibana, Y., Kurisawa, M., Uyama, H., Kakuchi, T., Kobayashi, S.
Chemistry Letters, 32, 4, 374-375, 2003
Laccase-catalyzed Synthesis and Antioxidant Property of Poly(catechin)
Kurisawa, M., Chung, J.E., Uyama, H., Kobayashi, S.
Macromolecular Bioscience, 3, 12, -, 2003
Regioselective Synthesis and Structures of (+)-Catechin-Aldehyde Polycondensates
Kim, Y.-J., Chung, J.E., Kurisawa, M., Uyama, H., Kobayashi, S.
Macromolecular Chemistry and Physics, 204, 15, -, 2003
Thermo- and pH-responsive biodegradable poly(α-N-substituted γ-glutamine)s
Tachibana, Y., Kurisawa, M., Uyama, H., Kobayashi, S.
Biomacromolecules, 4, 5, -, 2003
Enzymatic synthesis and antioxidant property of gelatin-catechin conjugates
Chung, J.E., Kurisawa, M., Uyama, H., Kobayashi, S.
Biotechnology Letters, 25, 23, -, 2003
Antioxidant Polymer Particles. Enzymatic Immobilization of Catechin on Polymer Particles
Ihara, N., Tachibana, Y., Chung, J.E., Kurisawa, M., Uyama, H., Kobayashi, S.
Chemistry Letters, 32, 9, 816-817, 2003
Amplification of antioxidant activity and xanthine oxidase inhibition of catechin by enzymatic polymerization
Kurisawa, M., Chung, J.E., Kim, Y.J., Uyama, H., Kobayashi, S.
Biomacromolecules, 4, 3, -, 2003
Enzymatic synthesis and antioxidant property of poly(allylamine)-catechin conjugate
Chung, J.E., Kurisawa, M., Tachibana, Y., Uyama, H., Kobayashi, S.
Chemistry Letters, 32, 7, 620-621, 2003
Biodegradable thermoresponsive poly(amino acid)s
Tachibana, Y., Kurisawa, M., Uyama, H., Kakuchi, T., Kobayashi, S.
Chemical Communications, 1, -, 2003
Enzymatic synthesis and antioxidant properties of poly(rutin)
Kurisawa, M., Chung, J.E., Uyama, H., Kobayashi, S.
Biomacromolecules, 4, 5, -, 2003
Influential factors on temperature-controlled gene expression using thermoresponsive polymeric gene carriers
Yokoyama, M., Kurisawa, M., Okano, T.
Journal of Artificial Organs, 4, 2, -, 2001
Gene expression control by temperature with thermo-responsive polymeric gene carriers
Kurisawa, M., Yokoyama, M., Okano, T.
Journal of Controlled Release, 69, 1, 127-137, 2000
Transfection efficiency increases by incorporating hydrophobic monomer units into polymeric gene carriers
Kurisawa, M., Yokoyama, M., Okano, T.
Journal of Controlled Release, 68, 1, 1-8, 2000
Modulated degradation of hydrogels with thermo-responsive network in relation to their swelling behavior
Kurisawa, M., Matsuo, Y., Yui, N.
Macromolecular Chemistry and Physics, 199, 4, -, 1998
Modulated degradation of hydrogels with thermo-responsive polymers
Kurisawa, M., Yui, N.
Proceedings of the Controlled Release Society, 25, -, 1998
Thermally switchable polyrotaxane as a model of stimuli-responsive supramolecules for nano-scale devices
Fujita, H., Ooya, T., Kurisawa, M., Mori, H., Terano, M., Yui, N.
Macromolecular Rapid Communications, 17, 8, -, 1996
Design of double diagnostic function using biodegradable hydrogels with interpenetrating polymer networks
Yui, N., Kurisawa, M.
Japanese Journal of Artificial Organs, 25, 1, -, 1996
Recent trends in drug delivery systems using biomaterials
Kurisawa, M., Yui, N.
Nippon rinsho. Japanese journal of clinical medicine, 54, 7, -, 1996