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山口 拓実 (YAMAGUCHI, Takumi)准教授
マテリアルサイエンス系, 生命機能工学領域, 超越バイオ医工学研究拠点

発表論文

48件
Comprehensive characterization of oligosaccharide conformational ensembles with conformer classification by free-energy landscape via reproductive kernel Hilbert space
Tokio Watanabe, Hirokazu Yagi, Saeko Yanaka, Takumi Yamaguchi, Koichi Kato
Physical Chemistry Chemical Physics, 23, 9753-9760, 2021
Field-stepwise-swept QCPMG solid-state 115In NMR of indium oxide
Kazuhiko Yamada, Takumi Yamaguchi, Ryutaro Ohashi, Shinobu Ohki, Kenzo Deguchi, Kenjiro Hashi, Atsushi Goto, Tadashi Shimizu
Solid State Nuclear Magnetic Resonance, 109, 101688-101688, 2020
Solid-state 17O NMR analysis of synthetically 17O-enriched d-glucosamine
Kazuhiko Yamada, Yoshiki Yamaguchi, Yoshinori Uekusa, Kazumasa Aoki, Ichio Shimada, Takumi Yamaguchi, Koichi Kato
Chemical Physics Letters, 749, 137455-137455, 2020
Remodeling of the Oligosaccharide Conformational Space in the Prebound State To Improve Lectin-Binding Affinity
Tatsuya Suzuki, Saeko Yanaka, Tokio Watanabe, Gengwei Yan, Tadashi Satoh, Hirokazu Yagi, Takumi Yamaguchi, Koichi Kato
Biochemistry, 34, 3180-3185, 2020
Dynamic Views of the Fc Region of Immunoglobulin G Provided by Experimental and Computational Observations.
Saeko Yanaka, Rina Yogo, Rintaro Inoue, Masaaki Sugiyama, Satoru G Itoh, Hisashi Okumura, Yohei Miyanoiri, Hirokazu Yagi, Tadashi Satoh, Takumi Yamaguchi, Koichi Kato
Antibodies (Basel, Switzerland), 8, 3, -, 2019
レクチン-糖鎖相互作用の物理化学的理解 核磁気共鳴分光法と分子動力学計算を通じて観る糖鎖の動的構造とレクチンの糖鎖認識の理解
矢木 宏和, 鈴木 達哉, 谷中 冴子, 山口 拓実, 加藤 晃一
医学のあゆみ, 269, 9, 761-767, 2019
Synthetic Approach to biomolecular science by cyborg supramolecular chemistry
Kensuke Kurihara, Muneyuki Matsuo, Takumi Yamaguchi, Sota Sato
Biochimica et Biophysica Acta - General Subjects, 1862, 2, 358-364, 2018
Lewis X-Carrying Neoglycolipids Evoke Selective Apoptosis in Neural Stem Cells.
Hirokazu Yagi, Gengwei Yan, Tatsuya Suzuki, Shingo Tsuge, Takumi Yamaguchi, Koichi Kato
Neurochemical research, 43, 1, 212-218, 2018
NMR characterization of the dynamic conformations of oligosaccharides
K. Kato, H. Yagi, T. Yamaguchi
Modern Magnetic Resonance (G. Webb eds), Springer, 737-754, 2018
分子動力学計算とNMR計測を用いた糖鎖の配座空間探査
山口 拓実, 渡邉 東紀男, 矢木 宏和, 加藤 晃一
JOURNAL OF COMPUTER CHEMISTRY-JAPAN, 17, 1, 1-7, 2018
Conformational effects of N-glycan core fucosylation of immunoglobulin G Fc region on its interaction with Fcγ receptor IIIa.
Sakae Y, Satoh T, Yagi H, Yanaka S, Yamaguchi T, Isoda Y, Iida S, Okamoto Y, Kato K
Scientific reports, 7, 1, 13780-13780, 2017
Hyper-Assembly of Self-Assembled Glycoclusters Mediated by Specific Carbohydrate-Carbohydrate Interactions
Gengwei Yan, Takumi Yamaguchi, Tatsuya Suzuki, Saeko Yanaka, Sota Sato, Makoto Fujita, Koichi Kato
CHEMISTRY-AN ASIAN JOURNAL, 12, 9, 968-972, 2017
Conformational Analysis of a High-Mannose-Type Oligosaccharide Displaying Glucosyl Determinant Recognised by Molecular Chaperones Using NMR-Validated Molecular Dynamics Simulation.
Tatsuya Suzuki, Megumi Kajino, Saeko Yanaka, Tong Zhu, Hirokazu Yagi, Tadashi Satoh, Takumi Yamaguchi, Koichi Kato
Chembiochem : a European journal of chemical biology, 18, 4, 396-401, 2017
Application of Site-Specific Spin Labeling for NMR Detecting Inhibitor-Induced Conformational Change of HIV-1 Reverse Transcriptase
Supaporn Seetaha, Maho Yagi-Utsumi, Takumi Yamaguchi, Kentaro Ishii, Supa Hannongbua, Kiattawee Choowongkomon, Koichi Kato
CHEMMEDCHEM, 11, 4, 363-366, 2016
Structural basis for two-step glucose trimming by glucosidase II involved in ER glycoprotein quality control
Tadashi Satoh, Takayasu Toshimori, Gengwei Yan, Takumi Yamaguchi, Koichi Kato
SCIENTIFIC REPORTS, 6, 20575-, 2016
A Hybrid Strategy for the Preparation of C-13-labeled High-mannose-type Oligosaccharides with Terminal Glucosylation for NMR Study
Tong Zhu, Takumi Yamaguchi, Tadashi Satoh, Koichi Kato
CHEMISTRY LETTERS, 44, 12, 1744-1746, 2015
Backbone (1)H, (13)C, and (15)N resonance assignments of the Fc fragment of human immunoglobulin G glycoprotein.
Hirokazu Yagi, Ying Zhang, Maho Yagi-Utsumi, Takumi Yamaguchi, Shigeru Iida, Yoshiki Yamaguchi, Koichi Kato
Biomolecular NMR assignments, 9, 2, 257-60, 2015
Paramagnetic NMR probes for characterization of the dynamic conformations and interactions of oligosaccharides
Koichi Kato, Takumi Yamaguchi
GLYCOCONJUGATE JOURNAL, 32, 7, 505-513, 2015
NMR characterization of HIV-1 reverse transcriptase binding to various non-nucleoside reverse transcriptase inhibitors with different activities
Ratsupa Thammaporn, Maho Yagi-Utsumi, Takumi Yamaguchi, Pornthip Boonsri, Patchreenart Saparpakorn, Kiattawee Choowongkomon, Supanna Techasakul, Koichi Kato, Supa Hannongbua
SCIENTIFIC REPORTS, 5, 15806-, 2015
A Self-Assembled Spherical Complex Displaying a Gangliosidic Glycan Cluster Capable of Interacting with Amyloidogenic Proteins
Sota Sato, Yutaka Yoshimasa, Daishi Fujita, Maho Yagi-Utsumi, Takumi Yamaguchi, Koichi Kato, Makoto Fujita
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 54, 29, 8435-8439, 2015
NMR-based structural validation of therapeutic antibody produced in Nicotiana benthamiana.
Hirokazu Yagi, Noriho Fukuzawa, Yasushi Tasaka, Kouki Matsuo, Ying Zhang, Takumi Yamaguchi, Sachiko Kondo, Shiori Nakazawa, Noritaka Hashii, Nana Kawasaki, Takeshi Matsumura, Koichi Kato
Plant cell reports, 34, 6, 959-68, 2015
Stable isotope labeling of glycoprotein expressed in silkworms using immunoglobulin G as a test molecule.
Hirokazu Yagi, Masatoshi Nakamura, Jun Yokoyama, Ying Zhang, Takumi Yamaguchi, Sachiko Kondo, Jun Kobayashi, Tatsuya Kato, Enoch Y Park, Shiori Nakazawa, Noritaka Hashii, Nana Kawasaki, Koichi Kato
Journal of biomolecular NMR, 62, 2, 157-67, 2015
A Self-Assembled Spherical Complex Displaying a Gangliosidic Glycan Cluster Capable of Interacting with Amyloidogenic Proteins
Sota Sato, Yutaka Yoshimasa, Daishi Fujita, Maho Yagi-Utsumi, Takumi Yamaguchi, Koichi Kato, Makoto Fujita
Angewandte Chemie, 127, 29, 8555-8559, 2015
Paramagnetism-assisted nuclear magnetic resonance analysis of dynamic conformations and interactions of oligosaccharides
Takumi Yamaguchi, Koichi Kato
Glycoscience: Biology and Medicine, 1, 137-145, 2015
Conformational Dynamics of Oligosaccharides Characterized by Paramagnetism-Assisted NMR Spectroscopy in Conjunction with Molecular Dynamics Simulation
Ying Zhang, Takumi Yamaguchi, Tadashi Satoh, Maho Yagi-Utsumi, Yukiko Kamiya, Yoshitake Sakae, Yuko Okamoto, Koichi Kato
BIOCHEMICAL ROLES OF EUKARYOTIC CELL SURFACE MACROMOLECULES, 842, 217-230, 2015
Conformational Dynamics of Oligosaccharides Characterized by Paramagnetism-Assisted NMR Spectroscopy in Conjunction with Molecular Dynamics Simulation
Ying Zhang, Takumi Yamaguchi, Tadashi Satoh, Maho Yagi-Utsumi, Yukiko Kamiya, Yoshitake Sakae, Yuko Okamoto, Koichi Kato
BIOCHEMICAL ROLES OF EUKARYOTIC CELL SURFACE (MACROMOLECULES), 842, 217-230, 2015
A self-assembled, π-stacked complex as a finely-tunable magnetic aligner for biomolecular NMR applications.
Sato S, Takeuchi R, Yagi-Utsumi M, Yamaguchi T, Yamaguchi Y, Kato K, Fujita M
Chemical communications (Cambridge, England), 51, 13, 2540-2543, 2015
Exploration of Conformational Spaces of High-Mannose-Type Oligosaccharides by an NMR-Validated Simulation
Takumi Yamaguchi, Yoshitake Sakae, Ying Zhang, Sayoko Yamamoto, Yuko Okamoto, Koichi Kato
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 53, 41, 10941-10944, 2014
Structural Basis for Disparate Sugar-Binding Specificities in the Homologous Cargo Receptors ERGIC-53 and VIP36
Tadashi Satoh, Kousuke Suzuki, Takumi Yamaguchi, Koichi Kato
PLOS ONE, 9, 2, e87963-, 2014
Conformational characterization of a protein complex involving intrinsically disordered protein by small-angle neutron scattering using the inverse contrast matching method: a case study of interaction between alpha-synuclein and PbaB tetramer as a model chaperone
Masaaki Sugiyama, Hirokazu Yagi, Takumi Yamaguchi, Kentaro Kumoi, Mitsuhiro Hirai, Yojiro Oba, Nobuhiro Sato, Lionel Porcar, Anne Martel, Koichi Kato
JOURNAL OF APPLIED CRYSTALLOGRAPHY, 47, 430-435, 2014
Structural analysis of oligosaccharides and glycoconjugates using NMR.
Yamaguchi Y, Yamaguchi T, Kato K
Advances in neurobiology, 9, 165-183, 2014
Preparation of water-soluble glycoconjugated poly(acrylamide) for NMR analyses of carbohydrate-carbohydrate interactions
Trinh Anh Xuan, Phan Nghia Trung, Bui Long Dinh, Takumi Yamaguchi, Koichi Kato
PROCEEDINGS OF PPS-29: THE 29TH INTERNATIONAL CONFERENCE OF THE POLYMER - CONFERENCE PAPERS, 1593, 347-349, 2014
Total synthesis and characterization of thielocin B1 as a protein-protein interaction inhibitor of PAC3 homodimer
Takayuki Doi, Masahito Yoshida, Kosuke Ohsawa, Kazuo Shin-ya, Motoki Takagi, Yoshinori Uekusa, Takumi Yamaguchi, Koichi Kato, Takatsugu Hirokawa, Tohru Natsume
CHEMICAL SCIENCE, 5, 5, 1860-1868, 2014
New NMR Tools for Characterizing the Dynamic Conformations and Interactions of Oligosaccharides
Ying Zhang, Takumi Yamaguchi, Koichi Kato
CHEMISTRY LETTERS, 42, 12, 1455-1462, 2013
Terminal Spin Labeling of a High-mannose-type Oligosaccharide for Quantitative NMR Analysis of Its Dynamic Conformation
Takumi Yamaguchi, Yukiko Kamiya, Yeun-Mun Choo, Sayoko Yamamoto, Koichi Kato
CHEMISTRY LETTERS, 42, 5, 544-546, 2013
Application of Metabolic 13C Labeling in Conjunction with High-Field Nuclear Magnetic Resonance Spectroscopy for Comparative Conformational Analysis of High Mannose-Type Oligosaccharides.
Yukiko Kamiya, Kotaro Yanagi, Toshihiko Kitajima, Takumi Yamaguchi, Yasunori Chiba, Koichi Kato
Biomolecules, 3, 1, 108-23, 2013
Ganglioside-embedding small bicelles for probing membrane-landing processes of intrinsically disordered proteins
Takumi Yamaguchi, Tsuyoshi Uno, Yoshinori Uekusa, Maho Yagi-Utsumi, Koichi Kato
CHEMICAL COMMUNICATIONS, 49, 12, 1235-1237, 2013
Lanthanide-assisted NMR evaluation of a dynamic ensemble of oligosaccharide conformations
Sayoko Yamamoto, Ying Zhang, Takumi Yamaguchi, Tomoshi Kameda, Koichi Kato
CHEMICAL COMMUNICATIONS, 48, 39, 4752-4754, 2012
Paramagnetic Lanthanide Tagging for NMR Conformational Analyses of N-Linked Oligosaccharides
Sayoko Yamamoto, Takumi Yamaguchi, Mate Erdelyi, Christian Griesinger, Koichi Kato
CHEMISTRY-A EUROPEAN JOURNAL, 17, 34, 9280-9282, 2011
Fluorous Pores in Coordination Networks
Minsul Jang, Takumi Yamaguchi, Kazuaki Ohara, Masaki Kawano, Makoto Fujita
CHEMISTRY-AN ASIAN JOURNAL, 4, 10, 1524-1526, 2009
Asymmetric [2+2] olefin cross photoaddition in a self-assembled host with remote chiral auxiliaries
Yuki Nishioka, Takumi Yamaguchi, Masaki Kawano, Makoto Fujita
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130, 26, 8160-+, 2008
Highly selective photomediated 1,4-radical addition to o-quinones controlled by a self-assembled cage
Takumi Yamaguchi, Makoto Fujita
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47, 11, 2067-2069, 2008
Unusual [2+4] and [2+2] cycloadditions of arenes in the confined cavity of self-assembled cages
Yuki Nishioka, Takumi Yamaguchi, Michito Yoshizawa, Makoto Fujita
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 129, 22, 7000-+, 2007
Self-assembly and host-guest chemistry of a 3.5-nm coordination nanotube
Takumi Yamaguchi, Shohei Tashiro, Masahide Tominaga, Masaki Kawano, Tomoji Ozeki, Makoto Fujita
CHEMISTRY-AN ASIAN JOURNAL, 2, 4, 468-476, 2007
A 3.5-nm coordination nanotube
T Yamaguchi, S Tashiro, M Tominaga, M Kawano, T Ozeki, M Fujita
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 126, 35, 10818-10819, 2004