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MATSUMURA, Kazuaki Professor, Director of Research Center for Exponential Biomedical DX, Director of Materials Chemistry Frontiers Research Area
Materials Science, Materials Chemistry Frontiers, Research Center for Biological Function and Sensory Information, Research Center for Exponential Biomedical DX (Excellent Core)

Published Papers

144 items
Design of Highly Selective Zn-Coordinated Polyampholyte for Cancer Treatment and Inhibition of Tumor Metastasis.
Nishant Kumar, Tadashi Nakaji-Hirabayashi, Moe Kato, Kazuaki Matsumura, Robin Rajan
Biomacromolecules, 25, 3, 1481-1490, 2024
Cryopreservation of rat embryos at all developmental stages by small-volume vitrification procedure and rapid warming in cryotubes.
Shinsuke Seki, Toshiaki Kawabe, Wataru Yamazaki, Kazuaki Matsumura, Takanori Oikawa, Takahiro Obata, Misako Higashiya, Megumi Yano, Tomoo Eto
Scientific reports, 13, 1, 20903-20903, 2023
Optogenetic Calcium Ion Influx in Myoblasts and Myotubes by Near-Infrared Light Using Upconversion Nanoparticles
Daisuke Maemura, The Son Le, Mari Takahashi, Kazuaki Matsumura, Shinya Maenosono
ACS Applied Materials & Interfaces, -, 2023
Enhancing the Mechanical Properties of Poly(vinyl alcohol) Fibers by Lithium Iodide Addition
Yusuke Taoka, Riza Asmaa Saari, Takumitsu Kida, Masayuki Yamaguchi, Kazuaki Matsumura
ACS Omega, 8, 36, 32623-32634, 2023
Polyampholytes and Their Hydrophobic Derivatives as Excipients for Suppressing Protein Aggregation.
Xianda Dai, Dandan Zhao, Kazuaki Matsumura, Robin Rajan
ACS applied bio materials, 6, 7, 2738-2746, 2023
Polyampholyte-Based Polymer Hydrogels for the Long-Term Storage, Protection and Delivery of Therapeutic Proteins.
Robin Rajan, Nishant Kumar, Dandan Zhao, Xianda Dai, Keiko Kawamoto, Kazuaki Matsumura
Advanced healthcare materials, 12, 17, e2203253-, 2023
Design of self-assembled glycopolymeric zwitterionic micelles as removable protein stabilizing agents.
Robin Rajan, Kazuaki Matsumura
Nanoscale advances, 5, 6, 1767-1775, 2023
Successful production of offspring derived from mouse zygotes vitrified with carboxylated ε-poly-L-lysine and polyvinyl alcohol without serum.
Midori Ishii, Maki Kamoshita, Yoshihiro Kurihara, Kazuaki Matsumura, Suong-Hyu Hyon, Junya Ito, Naomi Kashiwazaki
The Journal of reproduction and development, 69, 1, 53-55, 2023
Bridging polymer chemistry and cryobiology
Kazuaki Matsumura, Robin Rajan, Sana Ahmed
POLYMER JOURNAL, 55, 2, 105-115, 2023
Improved fertility of frozen-thawed porcine spermatozoa with 3,3-dimethylglutaric anhydride poly-L-lysine as a novel cryoprotectant.
Hansol Jin, Wooyoon Choi, Kazuaki Matsumura, Suong-Hyu Hyon, Yuki Gen, Masakazu Hayashi, Tadahiro Kawabata, Moe Ijiri, Kazuchika Miyoshi
Animal science journal = Nihon chikusan Gakkaiho, 94, 1, e13821-, 2023
Mechanistic insights and importance of hydrophobicity in cationic polymers for cancer therapy
Nishant Kumar, Kenji Oqmhula, Kenta Hongo, Kengo Takagi, Shin-ichi Yusa, Robin Rajan, Kazuaki Matsumura
Journal of Materials Chemistry B, 11, 7, 1456-1468, 2023
Evaluation of the optimal dose for maximizing the anti-adhesion performance of a self-degradable dextran-based material
Woogi Hyon, Suong-Hyu Hyon, Kazuaki Matsumura
Carbohydrate Polymer Technologies and Applications, -, 2022
Cryopreservation of pig spermatozoa using carboxylated poly-L-lysine as cryoprotectant.
Hansol Jin, Wooyoon Choi, Kazuaki Matsumura, Suong-Hyu Hyon, Yuki Gen, Masakazu Hayashi, Tadahiro Kawabata, Moe Ijiri, Kazuchika Miyoshi
The Journal of reproduction and development, 68, 5, 312-317, 2022
Cellular Flocculation Driven by Concentrated Polymer Brush-Modified Cellulose Nanofibers with Different Surface Charges.
Chiaki Yoshikawa, Keita Sakakibara, Punnida Nonsuwan, Miwako Shobo, Xida Yuan, Kazuaki Matsumura
Biomacromolecules, 23, 8, 3186-3197, 2022
Enhanced proliferation and differentiation of human mesenchymal stem cells in the gravity-controlled environment.
Tadashi Nakaji-Hirabayashi, Kazuaki Matsumura, Reiichi Ishihara, Tatsuya Ishiguro, Hiromitsu Nasu, Masatsugu Kanno, Shunji Ichida, Toshikatsu Hatashima
Artificial organs, 46, 9, 1760-1770, 2022
Cell-adhesive gels made of sacran/collagen complexes
Kenji Takada, Asuka Komuro, Mohammad Asif Ali, Maninder Singh, Maiko Okajima, Kazuaki Matsumura, Tatsuo Kaneko
Polymer Journal, -, 2022
Cellular Flocculation Using Concentrated Polymer Brush-Modified Cellulose Nanofibers with Different Fiber Lengths.
Xida Yuan, Punnida Nonsuwan, Miwako Shobo, Robin Rajan, Tomohiko Yamazaki, Keita Sakakibara, Kazuaki Matsumura, Chiaki Yoshikawa
Biomacromolecules, 23, 3, 1101-1111, 2022
Elucidating the degradation mechanism of a self-degradable dextran-based medical adhesive.
Woogi Hyon, Shuji Shibata, Etsuo Ozaki, Motoki Fujimura, Suong-Hyu Hyon, Kazuaki Matsumura
Carbohydrate polymers, 278, 118949-118949, 2022
Facile Photolithographic Fabrication of Zwitterionic Polymer Microneedles with Protein Aggregation Inhibition for Transdermal Drug Delivery
Harit Pitakjakpipop, Robin Rajan, Kittipong Tantisantisom, Pakorn Opaprakasit, Duy Dang Nguyen, Van Anh Ho, Kazuaki Matsumura, Paisan Khanchaitit
Biomacromolecules, 23, 1, 365-376, 2022
Quick and Mild Isolation of Intact Lysosomes Using Magnetic–Plasmonic Hybrid Nanoparticles
The Son Le, Mari Takahashi, Noriyoshi Isozumi, Akio Miyazato, Yuichi Hiratsuka, Kazuaki Matsumura, Tomohiko Taguchi, Shinya Maenosono
ACS Nano, 16, 1, 885-896, 2022
Polyethylene-glycol-modified zwitterionic polymer assisted protein aggregation arrest and refolding
Alisha Debas, Kazuaki Matsumura, Robin Rajan
Molecular Systems Design & Engineering, -, 2022
Development and structural analysis of dual-thermo-responsive self-assembled zwitterionic micelles
Dandan Zhao, Robin Rajan, Shin-ichi Yusa, Masaru Nakada, Kazuaki Matsumura
Materials Advances, -, 2022
Avengers against cancer: A new era of nano-biomaterial-based therapeutics
Nishant Kumar, Sajid Fazal, Eijiro Miyako, Kazuaki Matsumura, Robin Rajan
MATERIALS TODAY, 51, 317-349, 2021
Gene expression analysis of human induced pluripotent stem cells cryopreserved by vitrification using StemCell Keep
Akemi Ota, Suong-Hyu Hyon, Shoichiro Sumi, Kazuaki Matsumura
Biochemistry and Biophysics Reports, 28, 101172-101172, 2021
Molecular mechanisms of cell cryopreservation with polyampholytes studied by solid-state NMR
Kazuaki Matsumura, Fumiaki Hayashi, Toshio Nagashima, Robin Rajan, Suong-Hyu Hyon
Communications Materials, 2, 1, -, 2021
Design of an Ice Recrystallization-Inhibiting Polyampholyte-Containing Graft Polymer for Inhibition of Protein Aggregation
Robin Rajan, Nishant Kumar, Kazuaki Matsumura
Biomacromolecules, 23, 2, 487-496, 2021
Effect of different carboxylated poly L-lysine and dimethyl sulfoxide combinations on post thaw rabbit sperm functionality and fertility
Niyazi Kucuk, Sanan Raza, Kazuaki Matsumura, Ugur Ucan, Ilker Serin, Ahmet Ceylan, Melih Aksoy
CRYOBIOLOGY, 102, 127-132, 2021
Oxidized Polysaccharides as Green and Sustainable Biomaterials
Kazuaki Matsumura, Robin Rajan
Current Organic Chemistry, 25, 13, -, 2021
Small-volume vitrification and rapid warming yield high survivals of one-cell rat embryos in cryotubes†.
Yasuyoshi Fukuda, Misako Higashiya, Takahiro Obata, Keita Basaki, Megumi Yano, Kazuaki Matsumura, Kyoichi Ono, Takayoshi Ohba, Yosuke Okamoto, Kazutoshi Nishijima, Shinsuke Seki
Biology of reproduction, 105, 1, 258-266, 2021
Modification of poly(vinyl alcohol) fibers with lithium bromide
Riza Asmaa Saari, Ryota Maeno, Warinda Marujiwat, Muhammad Shahrulnizam Nasri, Kazuaki Matsumura, Masayuki Yamaguchi
Polymer, 213, -, 2021
Review of the current state of protein aggregation inhibition from a materials chemistry perspective: special focus on polymeric materials
Robin Rajan, Sana Ahmed, Neha Sharma, Nishant Kumar, Alisha Debas, Kazuaki Matsumura
Materials Advances, 2, 4, 1139-1176, 2021
Carboxylated ε-poly-L-lysine, a cryoprotective agent, is an effective partner of ethylene glycol for the vitrification of embryos at various preimplantation stages.
Yuki Kawasaki, Natsuki Kohaya, Yurie Shibao, Ayumi Suyama, Atsuko Kageyama, Katsuyoshi Fujiwara, Maki Kamoshita, Kazuaki Matsumura, Suong-Hyu Hyon, Junya Ito, Naomi Kashiwazaki
Cryobiology, 97, 245-249, 2020
Molecular design of polyampholytes for vitrification-induced preservation of three-dimensional cell constructs without using liquid nitrogen.
Kazuaki Matsumura, Sho Hatakeyama, Toshiaki Naka, Hiroshi Ueda, Robin Rajan, Daisuke Tanaka, Suong-Hyu Hyon
Biomacromolecules, 21, 8, 3017-3025, 2020
Development of an efficient vitrification method for chondrocyte sheets for clinical application
Asuka Hayashi, Miki Maehara, Ayuko Uchikura, Hitomi Matsunari, Kazuaki Matsumura, Suong-Hyu Hyon, Masato Sato, Hiroshi Nagashima
Regenerative Therapy, 14, 215-221, 2020
Novel anti-biofouling and drug releasing materials for contact lenses
Hiroaki Ogawa, Tadashi Nakaji-Hirabayashi, Kazuaki Matsumura, Chiaki Yoshikawa, Hiromi Kitano, Yoshiyuki Saruwatari
Colloids and Surfaces B: Biointerfaces, 189, 110859-110859, 2020
Cryoprotective Effect of Carboxylated Poly-L-lysine on the Chrysanthemum Shoot Tips
Daisuke Tanaka, Yoshinori Sakuma, Kazuaki Matsumura
Accepted, -, 2020
Special Issue: Nanocomposite Hydrogels for Biomedical Applications
Kazuaki Matsumura
Applied Sciences, 10, 1, 389-389, 2020
Controlling the degradation of cellulose scaffolds with Malaprade oxidation for tissue engineering
Wichchulada Chimpibul, Tadashi Nakaji-Hirabayashi, Xida Yuan, Kazuaki Matsumura
Journal of Materials Chemistry B, 8, 35, 7904-7913, 2020
Design of Stimuli-Responsive Polyampholytes and Their Transformation into Micro-Hydrogels for Drug Delivery
Robin Rajan, Nathapong Pangkom, Kazuaki Matsumura
ACS Symposium Series, 1350, 47-62, 2020
Cytosolic delivery of quantum dots mediated by freezing and hydrophobic polyampholytes in RAW 264.7 cells.
Ahmed S, Nakaji-Hirabayashi T, Rajan R, Zhao D, Matsumura K
Journal of materials chemistry. B, 7, 46, 7387-7395, 2019
Dual Thermo- and pH-Responsive Behavior of Double Zwitterionic Graft Copolymers for Suppression of Protein Aggregation and Protein Release
Dandan Zhao, Robin Rajan, Kazuaki Matsumura
ACS Applied Materials & Interfaces, 11, 43, 39459-39469, 2019
Comparative Study of Protein Aggregation Arrest by Zwitterionic Polysulfobetaines: Using Contrasting Raft Agents.
Sharma N, Rajan R, Makhaik S, Matsumura K
ACS omega, 4, 7, 12186-12193, 2019
Effect of dual‐drug‐releasing micelle–hydrogel composite on wound healing in vivo in full‐thickness excision wound rat model
Monika Patel, Tadashi Nakaji‐Hirabayashi, Kazuaki Matsumura
Journal of Biomedical Materials Research Part A, 107, 5, 1094-1106, 2019
Controlling the degradation of an oxidized dextran-based hydrogel independent of the mechanical properties
Punnida Nonsuwan, Akimasa Matsugami, Fumiaki Hayashi, Suong-Hyu Hyon, Kazuaki Matsumura
Carbohydrate Polymers, 204, 131-141, 2019
Micropatterned Cell Orientation of Cyanobacterial Liquid-Crystalline Hydrogels
Saranyoo Sornkamnerd, Maiko K. Okajima, Kazuaki Matsumura, Tatsuo Kaneko
ACS Applied Materials & Interfaces, 10, 51, 44834-44843, 2018
Development and Characterization of a Poly (Vinyl Alcohol)/Graphene Oxide Composite Hydrogel as An Artificial Cartilage Material
Yibo Zhao, Wataru Terai, Yuko Hoshijima, Kazuma Gotoh, Koji Matsuura, Kazuaki Matsumura
Applied Sciences, 8, 11, 2272-2272, 2018
Comparative analysis of the cellular entry of polystyrene and gold nanoparticles using the freeze concentration method
Sana Ahmed, Koyo Okuma, Kazuaki Matsumura
Biomaterials Science, 6, 7, 1791-1799, 2018
Surface-Selective Control of Cell Orientation on Cyanobacterial Liquid Crystalline Gels
Saranyoo Sornkamnerd, Maiko K. Okajima, Kazuaki Matsumura, Tatsuo Kaneko
ACS Omega, 3, 6, 6554-6559, 2018
pH-Responsive Polyion Complex Vesicle with Polyphosphobetaine Shells
Yuki Ohara, Keita Nakai, Sana Ahmed, Kazuaki Matsumura, Kazuhiko Ishihara, Shin Ichi Yusa
Langmuir, 35, 5, 1249-1256, 2018
Development and Application of Cryoprotectants.
Rajan R, Matsumura K
Advances in experimental medicine and biology, 1081, 339-354, 2018
Tunable Dual-Thermoresponsive Core-Shell Nanogels Exhibiting UCST and LCST Behavior
Robin Rajan, Kazuaki Matsumura
MACROMOLECULAR RAPID COMMUNICATIONS, 38, 22, -, 2017
Freezing-Assisted Gene Delivery Combined with Polyampholyte Nanocarriers
Sana Ahmed, Tadashi Nakaji-Hirabayashi, Takayoshi Watanabe, Takahiro Hohsaka, Kazuaki Matsumura
ACS BIOMATERIALS SCIENCE & ENGINEERING, 3, 8, 1677-1689, 2017
Freezing-Assisted Gene Delivery Combined with Polyampholyte Nanocarriers
Sana Ahmed, Tadashi Nakaji-Hirabayashi, Takayoshi Watanabe, Takahiro Hohsaka, Kazuaki Matsumura
ACS BIOMATERIALS SCIENCE & ENGINEERING, 3, 8, 1677-1689, 2017
Magnetic Separation of Autophagosomes from Mammalian Cells Using Magnetic-Plasmonic Hybrid Nanobeads
Mari Takahashi, Priyank Mohan, Kojiro Mukai, Yuichi Takeda, Takeo Matsumoto, Kazuaki Matsumura, Masahiro Takakura, Hiroyuki Arai, Tomohiko Taguchi, Shinya Maenosono
ACS OMEGA, 2, 8, 4929-4937, 2017
Facile preparation of transparent poly(vinyl alcohol) hydrogels with uniform microcrystalline structure by hot-pressing without using organic solvents
Tomoyo Sakaguchi, Shusaku Nagano, Mitsuo Hara, Suong-Hyu Hyon, Monika Patel, Kazuaki Matsumura
POLYMER JOURNAL, 49, 7, 535-542, 2017
A Freeze-Concentration and Polyampholyte-Modified Liposome-Based Antigen-Delivery System for Effective Immunotherapy
Sana Ahmed, Satoshi Fujita, Kazuaki Matsumura
ADVANCED HEALTHCARE MATERIALS, 6, 14, -, 2017
Switchable release nano-reservoirs for co-delivery of drugs via a facile micelle-hydrogel composite
Monika Patel, Tatsuo Kaneko, Kazuaki Matsumura
JOURNAL OF MATERIALS CHEMISTRY B, 5, 19, 3488-3497, 2017
Inhibition of protein aggregation by zwitterionic polymer-based core-shell nanogels
Robin Rajan, Kazuaki Matsumura
SCIENTIFIC REPORTS, 7, 45777-, 2017
Successful vitrification of pronuclear-stage pig embryos with a novel cryoprotective agent, carboxylated epsilon-poly-L-lysine
Maki Kamoshita, Tsubasa Kato, Katsuyoshi Fujiwara, Takafumi Namiki, Kazuaki Matsumura, Suong-Hyu Hyon, Junya Ito, Naomi Kashiwazaki
PLOS ONE, 12, 4, e0176711-, 2017
Tunable Phase-Separation Behavior of Thermoresponsive Polyampholytes Through Molecular Design
Esha Das, Kazuaki Matsumura
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 55, 5, 876-884, 2017
THE BENEFICIAL EFFECT OF CARBOXYLATED POLY-L-LYSINE ON CRYOSURVIVAL OF VITRIFIED EARLY STAGE EMBRYOS
Yuta Tsuji, Toshiroh Iwasaki, Hiromi Ogata, Yukiko Matsumoto, Shoji Kokeguchi, Kazuaki Matsumura, Suong-Hyu Hyon, Masahide Shiotani
CRYOLETTERS, 38, 1, 1-6, 2017
StemCell Keep (TM) Is Effective for Cryopreservation of Human Embryonic Stem Cells by Vitrification
Akemi Ota, Kazuaki Matsumura, Jun-Jae Lee, Shoichiro Sumi, Soung-Hyu Hyon
CELL TRANSPLANTATION, 26, 5, 773-787, 2017
Thixotropic injectable hydrogel using a polyampholyte and nanosilicate prepared directly after cryopreservation
Minkle Jain, Kazuaki Matsumura
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 69, 1273-1281, 2016
同種軟骨細胞シート移植を目指したガラス化凍結保存法の検討
前原 美樹, 佐藤 正人, 豊田 恵利子, 高橋 匠, 岡田 恵里, 滝澤 大智, 松村 和明, 玄 丞烋, 長嶋 比呂志, 持田 讓治
日本整形外科学会雑誌, 90, 8, S1530-S1530, 2016
Cryoprotection of fibroblasts by carboxylated poly-L-lysine upon repeated freeze/Thaw cycles
Oh Seong Jin, Jong Ho Lee, Yong Cheol Shin, Eun Ji Lee, Jun Jae Lee, Kazuaki Matsumura, Suong Hyu Hyon, Dong Wook Han
Cryo-Letters, 37, 396-403, 2016
Dextran Oxidized by a Malaprade Reaction Shows Main Chain Scission Through a Maillard Reaction Triggered by Schiff Base Formation Between Aldehydes and Amines
Wichchulada Chimpibul, Toshio Nagashima, Fumiaki Hayashi, Naoki Nakajima, Suong-Hyu Hyon, Kazuaki Matsumura
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 54, 14, 2254-2260, 2016
Cryopreservation of a Two-Dimensional Monolayer Using a Slow Vitrification Method with Polyampholyte to Inhibit Ice Crystal Formation
Kazuaki Matsumura, Keiko Kawamoto, Masahiro Takeuchi, Shigehiro Yoshimura, Daisuke Tanaka, Suong-Hyu Hyon
ACS BIOMATERIALS SCIENCE & ENGINEERING, 2, 6, 1023-1029, 2016
Polyampholyte- and nanosilicate-based soft bionanocomposites with tailorable mechanical and cell adhesion properties
Minkle Jain, Kazuaki Matsumura
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 104, 6, 1379-1386, 2016
Toward a Molecular Understanding of the Mechanism of Cryopreservation by Polyampholytes: Cell Membrane Interactions and Hydrophobicity
Robin Rajan, Fumiaki Hayashi, Toshio Nagashima, Kazuaki Matsumura
BIOMACROMOLECULES, 17, 5, 1882-1893, 2016
48 CARBOXYLATED ε-POLY-L-LYSINE (COOH-PLL) IMPROVES DEVELOPMENTAL ABILITY AND REDUCES MITOCHONDRIAL DAMAGE OF VITRIFIED PORCINE EMBRYOS AT THE PRONUCLEAR STAGE
M. Kamoshita, K. Fujiwara, K. Matsumura, S.-H. Hyon, J. Ito, N. Kashiwazaki
Reproduction, Fertility and Development, 28, 2, 154-154, 2016
Development of Novel Polymeric Cryoprotectants and Their Applications
松村 和明
Cryobiology and Cryotechnology, 62, 1, 11-15, 2016
Vitrification of Artificial Tissues: Current Progress and Future Possibilities
Nagashima Hiroshi, Maehara Miki, Katsumata Yuki, Uchikura Ayuko, Matsumura Kazuaki, Sato Masato, Matsunari Hitomi
Transactions of Japanese Society for Medical and Biological Engineering, 54, 26, S70-S70, 2016
Development of novel cryoprotectants and their application for tissue engineering
Matsumura Kazuaki
Transactions of Japanese Society for Medical and Biological Engineering, 54, 26, S69-S69, 2016
Biodegradable shape memory polymers functionalized with anti-biofouling interpenetrating polymer networks
I. Dueramae, M. Nishida, T. Nakaji-Hirabayashi, K. Matsumura, H. Kitano
JOURNAL OF MATERIALS CHEMISTRY B, 4, 32, 5394-5404, 2016
Biodegradable shape memory polymers functionalized with anti-biofouling interpenetrating polymer networks
I. Dueramae, M. Nishida, T. Nakaji-Hirabayashi, K. Matsumura, H. Kitano
Journal of Materials Chemistry B, 4, 32, 5394-5404, 2016
Ag/FeCo/Ag Core/Shell/Shell Magnetic Nanoparticles with Plasmonic Imaging Capability
Mari Takahashi, Priyank Mohan, Akiko Nakade, Koichi Higashimine, Derrick Mott, Tsutomu Hamada, Kazuaki Matsumura, Tomohiko Taguchi, Shinya Maenosono
LANGMUIR, 31, 7, 2228-2236, 2015
A zwitterionic polymer as a novel inhibitor of protein aggregation
Robin Rajan, Kazuaki Matsumura
JOURNAL OF MATERIALS CHEMISTRY B, 3, 28, 5683-5689, 2015
Self-degradation of tissue adhesive based on oxidized dextran and poly-L-lysine
Kazuaki Matsumura, Naoki Nakajima, Hajime Sugai, Suong-Hyu Hyon
CARBOHYDRATE POLYMERS, 113, 32-38, 2014
Low cytotoxic tissue adhesive based on oxidized dextran and epsilon-poly-L-lysine
Suong-Hyu Hyon, Naoki Nakajima, Hajime Sugai, Kazuaki Matsumura
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 102, 8, 2511-2520, 2014
Protein cytoplasmic delivery using polyampholyte nanoparticles and freeze concentration
Sana Ahmed, Fumiaki Hayashi, Toshio Nagashima, Kazuaki Matsumura
BIOMATERIALS, 35, 24, 6508-6518, 2014
Antifreeze Effect of Carboxylated epsilon-Poly-L-lysine on the Growth Kinetics of Ice Crystals
Dmitry A. Vorontsov, Gen Sazaki, Suong-Hyu Hyon, Kazuaki Matsumura, Yoshinori Furukawa
JOURNAL OF PHYSICAL CHEMISTRY B, 118, 34, 10240-10249, 2014
The effect of a novel cryoprotective agent, carboxylated epsilon-poly-L-lysine, on the developmental ability of re-vitrified mouse embryos at the pronuclear stage
Yurie Shibao, Katsuyoshi Fujiwara, Yuki Kawasaki, Kazuaki Matsumura, Suong-Hyu Hyon, Junya Ito, Naomi Kashiwazaki
CRYOBIOLOGY, 68, 2, 200-204, 2014
The effect of a novel cryoprotective agent, carboxylated epsilon-poly-L-lysine, on the developmental ability of re-vitrified mouse embryos at the pronuclear stage
Yurie Shibao, Katsuyoshi Fujiwara, Yuki Kawasaki, Kazuaki Matsumura, Suong-Hyu Hyon, Junya Ito, Naomi Kashiwazaki
CRYOBIOLOGY, 68, 2, 200-204, 2014
Biobased Polyimides from 4-Aminocinnamic Acid Photodimer
Phruetchika Suvannasara, Seiji Tateyama, Akio Miyasato, Kazuaki Matsumura, Tatsuya Shimoda, Takashi Ito, Yukiho Yamagata, Tomoya Fujita, Naoki Takaya, Tatsuo Kaneko
MACROMOLECULES, 47, 5, 1586-1593, 2014
Preparation of Novel Synthetic Cryoprotectants
RAJAN Robin, MATSUMURA Kazuaki
Cryobiology and cryotechnology, 60, 2, 99-103, 2014
Hydrogelation of dextran-based polyampholytes with cryoprotective properties via click chemistry
Minkle Jain, Robin Rajan, Suong-Hyu Hyon, Kazuaki Matsumura
BIOMATERIALS SCIENCE, 2, 3, 308-317, 2014
Hypothermicpreservation of Mouse Induced Pluripotent Stem Cells by Polyampholytes
Kazuaki Matsumura, HakHee Kim, Suong-Hyu Hyon
CURRENT NANOSCIENCE, 10, 2, 222-226, 2014
Efficient Production of Live Offspring from Mouse Oocytes Vitrified with a Novel Cryoprotective Agent, Carboxylated epsilon-poly-L-lysine
Hitomi Watanabe, Natsuki Kohaya, Maki Kamoshita, Katsuyoshi Fujiwara, Kazuaki Matsumura, Suong-Hyu Hyon, Junya Ito, Naomi Kashiwazaki
PLOS ONE, 8, 12, e83613-, 2013
Cryoprotective properties of completely synthetic polyampholytes via reversible addition-fragmentation chain transfer (RAFT) polymerization and the effects of hydrophobicity
Robin Rajan, Minkle Jain, Kazuaki Matsumura
Journal of Biomaterials Science, Polymer Edition, 24, 15, 1767-1780, 2013
Long-term cryopreservation of human mesenchymal stem cells using carboxylated poly-l-lysine without the addition of proteins or dimethyl sulfoxide
Kazuaki Matsumura, Fumiaki Hayashi, Toshio Nagashima, Suong Hyu Hyon
Journal of Biomaterials Science, Polymer Edition, 24, 12, 1484-1497, 2013
Development of a novel vitrification method for chondrocyte sheets
Miki Maehara, Masato Sato, Masahito Watanabe, Hitomi Matsunari, Mami Kokubo, Takahiro Kanai, Michio Sato, Kazuaki Matsumura, Suong-Hyu Hyon, Munetaka Yokoyama, Joji Mochida, Hiroshi Nagashima
BMC BIOTECHNOLOGY, 13, 58-, 2013
Cryoprotective Polyampholytes Hydrogel
MATSUMURA Kazuaki
Cryobiology and cryotechnology, 59, 2, 111-115, 2013
Cryoprotection of fibroblasts by carboxylated poly-L-lysine upon repeated freeze/thaw cycles
Oh Seong Jin, Jong Ho Lee, Yong Cheol Shin, Eun Ji Lee, Jun Jae Lee, Kazuaki Matsumura, Suong-Hyu Hyon, Dong-Wook Han
Cryo-Letters, 34, 4, 396-403, 2013
Cryoprotection of fibroblasts by carboxylated poly-L-lysine upon repeated freeze/thaw cycles
Oh Seong Jin, Jong Ho Lee, Yong Cheol Shin, Eun Ji Lee, Jun Jae Lee, Kazuaki Matsumura, Suong-Hyu Hyon, Dong-Wook Han
Cryo-Letters, 34, 4, 396-403, 2013
Cell encapsulation and cryostorage in PVA-gelatin cryogels: incorporation of carboxylated e-poly-L-lysine as cryoprotectant
Nihal E. Vrana, Kazuaki Matsumura, Suong-Hyu Hyon, Luke M. Geever, James E. Kennedy, John G. Lyons, Clement L. Higginbotham, Paul A. Cahill, Garrett B. McGuinness
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 6, 4, 280-290, 2012
Attenuation of Murine Graft-Versus-Host Disease by a Tea Polyphenol
Jun Kanamune, Yasuhiro Iwanaga, Tatsuo Kina, Hirofumi Noguchi, Kazuaki Matsumura, Shinji Uemoto, Suong-Hyu Hyon
CELL TRANSPLANTATION, 21, 5, 909-918, 2012
Effective vitrification of human induced pluripotent stem cells using carboxylated epsilon-poly-L-lysine
Kazuaki Matsumura, Jung Yoon Bae, Hak Hee Kim, Suong Hyu Hyon
CRYOBIOLOGY, 63, 2, 76-83, 2011
A preliminary in vivo study of artificial meniscus using the uniaxial oriented reinforced compressive polyvinyl alcohol hydrogel
Masanori Kobayashi, Kazuaki Matsumura, Hyon Suong Hyu
Trends in Biomaterials and Artificial Organs, 25, 107-111, 2011
Epigallocatechin-3-gallate protects kidneys from ischemia reperfusion injury by HO-1 upregulation and inhibition of macrophage infiltration
Yoichi Kakuta, Masayoshi Okumi, Yoshitaka Isaka, Koichi Tsutahara, Toyofumi Abe, Koji Yazawa, Naotsugu Ichimaru, Kazuaki Matsumura, Suong-Hyu Hyon, Shiro Takahara, Norio Nonomura
TRANSPLANT INTERNATIONAL, 24, 5, 514-522, 2011
EPIGALLOCATECHIN-3-GALLATE PROTECTS KIDNEYS FROM ISCHEMIA REPERFUSION INJURY BY INHIBITION OF MACROPHAGE INFILTRATION
Yoichi Kakuta, Masayoshi Okumi, Koichi Tsutahara, Toyofumi Abe, Koji Yazawa, Kazuaki Matsumura, Suong-Hyu Hyon, Shiro Takahara, Norio Nonomura
JOURNAL OF UROLOGY, 185, 4, E902-E902, 2011
Oral pretreatment with a green tea polyphenol for cardioprotection against ischemia-reperfusion injury in an isolated rat heart model
Shigeki Yanagi, Kazuaki Matsumura, Akira Marui, Manabu Morishima, Suong-Hyu Hyon, Tadashi Ikeda, Ryuzo Sakata
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 141, 2, 511-517, 2011
In vivo cancer targeting of water-soluble taxol by folic acid immobilization
Junichi Nakamura, Naoki Nakajima, Kazuaki Matsumura, Suong-Hyu Hyon
Journal of Nanomedicine and Nanotechnology, 2, 1, -, 2011
Application of the bactericidal activity of epsilon-poly-l-lysine to the storage of human platelet concentrates
Shigenori Tanaka, Tomoya Hayashi, Hidemi Tateyama, Kazuaki Matsumura, Suong-Hyu Hyon, Fumiya Hirayama
TRANSFUSION, 50, 4, 932-940, 2010
Control of proliferation and differentiation of osteoblasts on apatite-coated poly(vinyl alcohol) hydrogel as an artificial articular cartilage material
Kazuaki Matsumura, Takashi Hayami, Suong-Hyu Hyon, Sadarni Tsutsumi
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 92A, 4, 1225-1232, 2010
Water-soluble Taxol Conjugates with Dextran and Targets Tumor Cells by Folic Acid Immobilization
Junichi Nakamura, Naoki Nakajima, Kazuaki Matsumura, Suong-Hyu Hyon
ANTICANCER RESEARCH, 30, 3, 903-909, 2010
Nonfrozen Preservation of Articular Cartilage by Epigallocatechin-3-Gallate Reversibly Regulating Cell Cycle and NF-kappa B Expression
Jung Yoon Bae, Dong-Wook Han, Kazuaki Matsumura, Shigeyuki Wakitani, Masashi Nawata, Suong-Hyu Hyon
TISSUE ENGINEERING PART A, 16, 2, 595-603, 2010
Nonfrozen Preservation of Articular Cartilage by Epigallocatechin-3-Gallate Reversibly Regulating Cell Cycle and NF-kappa B Expression
Jung Yoon Bae, Dong-Wook Han, Kazuaki Matsumura, Shigeyuki Wakitani, Masashi Nawata, Suong-Hyu Hyon
TISSUE ENGINEERING PART A, 16, 2, 595-603, 2010
Effects of Epigallocatechin Gallate on Osteogenic Capability of Human Mesenchymal Stem Cells After Suspension in Phosphate-Buffered Saline
Kaori Kashiwa, Noriko Kotobuki, Mika Tadokoro, Kazuaki Matsumura, Suong-Hyu Hyon, Shinichi Yoshiya, Hajime Ohgushi
TISSUE ENGINEERING PART A, 16, 1, 91-100, 2010
Effects of Epigallocatechin Gallate on Osteogenic Capability of Human Mesenchymal Stem Cells After Suspension in Phosphate-Buffered Saline
Kaori Kashiwa, Noriko Kotobuki, Mika Tadokoro, Kazuaki Matsumura, Suong-Hyu Hyon, Shinichi Yoshiya, Hajime Ohgushi
TISSUE ENGINEERING PART A, 16, 1, 91-100, 2010
OP-361 (-)-epigallocatechin-3-gallateのラット腎阻血再灌灌流障害モデルにおける腎障害抑制効果(腎移植1,一般演題口演,第98回日本泌尿器科学会総会)
角田 洋一, 奥見 雅由, 斉藤 純, 蔦原 宏一, 阿部 豊文, 矢澤 浩治, 市丸 直嗣, 貝森 敦哉, 高原 史郎, 松村 和明, 玄 丞烋, 野々村 祝夫, 奥山 明彦
日本泌尿器科学会雑誌, 101, 2, 323-323, 2010
Polyampholytes as Cryoprotective Agents for Mammalian Cell Cryopreservation
Kazuaki Matsumura, Jung Yoon Bae, Suong Hyu Hyon
CELL TRANSPLANTATION, 19, 6-7, 691-699, 2010
Polyampholytes as low toxic efficient cryoprotective agents with antifreeze protein properties
Kazuaki Matsumura, Suong-Hyu Hyon
BIOMATERIALS, 30, 27, 4842-4849, 2009
Reversible Regulation of Cell Cycle-Related Genes by Epigallocatechin Gallate for Hibernation of Neonatal Human Tarsal Fibroblasts
Jung Yoon Bae, Jun Kanamune, Dong-Wook Han, Kazuaki Matsumura, Suong-Hyu Hyon
CELL TRANSPLANTATION, 18, 4, 459-469, 2009
Beneficial Storage Effects of Epigallocatechin-3-O-Gallate on the Articular Cartilage of Rabbit Osteochondral Allografts
Jung Yoon Bae, Kazuaki Matsumura, Shigeyuki Wakitani, Amu Kawaguchi, Sadami Tsutsumi, Suong-Hyu Hyon
CELL TRANSPLANTATION, 18, 5-6, 505-512, 2009
Long-Term Preservation of Rat Skin Tissue by Epigallocatechin-3-O-Gallate
HakHee Kim, Takeshi Kawazoe, Kazuaki Matsumura, Shigehiko Suzuki, Suong-Hyu Hyon
CELL TRANSPLANTATION, 18, 5-6, 513-519, 2009
Preservation of Platelets by Adding Epigallocatechin-3-O-Gallate to Platelet Concentrates
Kazuaki Matsumura, Hiroshi Takayama, Jung Yoon Bae, Mitsuru Kurihara, Sadami Tsutsumi, Suong-Hyu Hyon
CELL TRANSPLANTATION, 18, 5-6, 521-528, 2009
Enhanced antitumor activities of (-)-epigallocatechin-3-O-gallate fatty acid monoester derivatives in vitro and in vivo
Kazuaki Matsumura, Kunihiro Kaihatsu, Shuichi Mori, Han Hee Cho, Nobuo Kato, Suong Hyu Hyon
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 377, 4, 1118-1122, 2008
Time-dependent intracellular trafficking of FITC-conjugated epigallocatechin-3-O-gallate in L-929 cells
Dong-Wook Han, Kazuaki Matsumura, Bongju Kim, Suong-Hyu Hyon
BIOORGANIC & MEDICINAL CHEMISTRY, 16, 22, 9652-9659, 2008
ANTITUMOR ACTIVITY OF (-)-EPIGALLOCATECHIN-3-O-GALLATE FATTY ACID DERIVATIVES
Kunihiro Kaihatsu, Kazuaki Matsumura, Shuichi Mori, Han Hee Cho, Suong Hyu Hyon, Nobuo Kato
ANTICANCER RESEARCH, 28, 5C, 3338-3338, 2008
The behavior of vascular smooth muscle cells and platelets onto epigallocatechin gallate-releasing poly(L-lactide-co-epsilon-caprolactone) as stent-coating materials
Han Hee Cho, Dong-Wook Han, Kazuaki Matsumura, Sadami Tsutsumi, Suong-Hyu Hyon
BIOMATERIALS, 29, 7, 884-893, 2008
Effects on gingival cells of hydroxyapatite immobilized on poly(ethylene-co-vinyl alcohol)
Kazuaki Matsumura, Suong-Hyu Hyon, Naoki Nakajima, Sadami Tsutsumi
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 82A, 2, 288-295, 2007
Imparting cell adhesion to poly(vinyl alcohol) hydrogel by coating with hydroxyapatite thin film
Takashi Hayami, Kazuaki Matsumura, Masanobu Kusunoki, Hiroaki Nishikawa, Shigeki Hontsu
MATERIALS LETTERS, 61, 13, 2667-2670, 2007
Pretreatment with epigallocatechin-3-gallate, green tea polyphenol, in oral uptake attenuates myocardial ischemia/reperfusion injury in a rat heart perfusion model
Shigeki Yanagi, Kazuaki Matsumura, Kiyoaki Takaba, Atsushi Nagasawa, Tetsuya Kamitani, Suong-Hyu Hyon, Tadashi Ikeda, Masashi Komeda
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 49, 9, 235A-235A, 2007
Hibernation, reversible cell growth inhibition by epigallocatechin-3-O-gallate
Kazuaki Matsumura, Jong-Yoon Kim, Sadami Tsutsumi, Suong-Hyu Hyon
JOURNAL OF BIOTECHNOLOGY, 127, 4, 758-764, 2007
Vascular smooth muscle cell behaviors onto epigallocatechin-3-O-gallate-blended L-lactide/epsilon-caprolactone copolymers
D. -W. Han, H. H. Cho, D. -Y. Jung, J. J. Lee, K. Matsumura, J. -C. Park, S. -H. Hyon
ASBM7: ADVANCED BIOMATERIALS VII, 342-343, 189-+, 2007
Degradation control of collagen by epigallocatechlin-3-O-gallate
Han Hee Cho, Kazuaki Matsunnura, Naoki Nakajima, Dong-Wook Han, Sadami Tsutsumi, Suong-Hyu Hyon
ASBM7: ADVANCED BIOMATERIALS VII, 342-343, 781-+, 2007
Selective bone formation on hydroxyapatite-granule-implanted titanium
Akira Watazu, Yingzhe Li, Sadami Tsutsumi, Kazuaki Matsumura, Naobumi Saito
BIOCERAMICS, VOL 19, PTS 1 AND 2, 330-332, 459-+, 2007
Tea polyphenol inhibits allostimulation in mixed lymphocyte culture
Jong-Yoon Kim, Tatsuo Kina, Yasuhiro Iwanaga, Hirofumi Noguchi, Kazuaki Matsumura, Suong-Hyu Hyon
CELL TRANSPLANTATION, 16, 1, 75-83, 2007
Graft pretreatment with green tea polyphenol, epigallocatechin-3-gallate, inhibits neo-intimal hyperplasia by inactivating mitogen-activated protein kinases in a rabbit vein graft model
Kiyoaki Takaba, Kazuaki Matsumura, Chunti Jiang, Shintaro Nemoto, Takeshi Shimamoto, Suong-Hyu Hyon, Tadashi Ikeda, Masashi Komeda
CIRCULATION, 114, 18, 475-475, 2006
Epigallocatechin-3-O-gallate As a Novel Preservation Additive for Tooth Transplantation
MATSUMURA Kazuaki, TSUTSUMI Sadami, HYON Suong-Hyu
Journal of oral tissue engineering, 3, 3, 125-130, 2006
Preservation of rat aortic tissue transplant with green tea polyphenols
S. -H. Hyon, D. -H. Kim, W. Cui, K. Matsumura, J. -Y. Kim, S. Tsutsumi
CELL TRANSPLANTATION, 15, 10, 881-883, 2006
Surface modification of poly(ethylene-co-vinyl alcohol): hydroxyapatite immobilization and control of periodontal ligament cells differentiation
K Matsumura, SH Hyon, N Nakajima, H Iwata, A Watazu, S Tsutsumi
BIOMATERIALS, 25, 19, 4817-4824, 2004
Attachment of Artificial Cartilage to Underlying Bone
Kazuyasu Ushio, Masanori Oka, Suong-Hyu Hyon, Takashi Hayami, Shigeto Yura, Kazuaki Matsumura, Junya Toguchida, Takashi Nakamura
Journal of Biomedical Materials Research - Part B Applied Biomaterials, 68, 1, 59-68, 2004
Attachment of artificial cartilage to underlying bone.
Ushio K, Oka M, Hyon SH, Hayami T, Yura S, Matsumura K, Toguchida J, Nakamura T
Journal of biomedical materials research. Part B, Applied biomaterials, 68, 1, 59-68, 2004
Adhesion between poly(ethylene-co-vinyl alcohol) (EVA) and titanium
K Matsumura, SH Hyon, N Nakajima, CY Peng, H Iwata, S Tsutsumi
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 60, 2, 309-315, 2002
Type I atelocollagen grafting onto ozone-treated polyurethane films: Cell attachment, proliferation, and collagen synthesis
JC Park, YS Hwang, JE Lee, KD Park, K Matsumura, SH Hyon, H Suh
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 52, 4, 669-677, 2000
Surface modification of poly(ethylene-co-vinyl alcohol) (EVA). Part I. Introduction of carboxyl groups and immobilization of collagen
Kazuaki Matsumura, Suong-Hyu Hyon, Naoki Nakajima, Chunyan Peng, Sadami Tsutsumi
Journal of Biomedical Materials Research, 50, 4, 512-517, 2000