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濱田 勉 (HAMADA, Tsutomu)准教授
マテリアルサイエンス系, 生命機能工学領域

発表論文

75件
Control of Lipid Bilayer Phases of Cell-Sized Liposomes by Surface-Engineered Plasmonic Nanoparticles.
Tomohiro Nobeyama, Kazuki Shigyou, Hirotaka Nakatsuji, Hiroshi Sugiyama, Naoko Komura, Hiromune Ando, Tsutomu Hamada, Tatsuya Murakami
Langmuir : the ACS journal of surfaces and colloids, 36, 26, 7741-7746, 2020
Osmotic-Tension-Induced Membrane Lateral Organization.
Nichaporn Wongsirojkul, Naofumi Shimokawa, Pakorn Opaprakasit, Masahiro Takagi, Tsutomu Hamada
Langmuir : the ACS journal of surfaces and colloids, 36, 11, 2937-2945, 2020
Mechano-Sensitive Synthetic Ion Channels
Takahiro Muraoka, Kaori Umetsu, Kazuhito V. Tabata, Tsutomu Hamada, Hiroyuki Noji, Takashi Yamashita, Kazushi Kinbara
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139, 49, 18016-18023, 2017
光に応答する遺伝子デリバリーシステム
長崎健, 濱田勉
レーザー研究, 45, 11, 696-700, 2017
人工細胞膜のダイナミクス解析と構造制御
濱田勉
応用物理, 86, 10, 875-880, 2017
Lateral Tension-Induced Penetration of Particles into a Liposome
Kazuki Shigyou, Ken H. Nagai, Tsutomu Hamada
MATERIALS, 10, 7, 765-765, 2017
Photoinduced Fusion of Lipid Bilayer Membranes
Yui Suzuki, Ken H. Nagai, Anatoly Zinchenko, Tsutomu Hamada
LANGMUIR, 33, 10, 2671-2676, 2017
Lateral Diffusion of a Submicrometer Particle on a Lipid Bilayer Membrane
Kazuki Shigyou, Ken H. Nagai, Tsutomu Hamada
LANGMUIR, 32, 51, 13771-13777, 2016
Penetration of Oxidized Carbon Nanospheres through Lipid Bilayer Membrane: Comparison to Graphene Oxide and Oxidized Carbon Nanotubes, and Effects of pH and Membrane Composition
Jiraporn Seemork, Titiporn Sansureerungsikul, Kamonluck Sathomsantikun, Tarit Sinthusake, Kazuki Shigyou, Thapakorn Tree-Udom, Banphot Jiangchareon, Khajeelak Chiablaem, Kriengsak Lirdprapamongkol, Jisnuson Svasti, Tsutomu Hamada, Tanapat Palaga, Supason Wanichwecharungruang
ACS APPLIED MATERIALS & INTERFACES, 8, 36, 23549-23557, 2016
Phase Diagrams and Ordering in Charged Membranes: Binary Mixtures of Charged and Neutral Lipids
Naofumi Shimokawa, Hiroki Himeno, Tsutomu Hamada, Masahiro Takagi, Shigeyuki Komura, David Andelman
JOURNAL OF PHYSICAL CHEMISTRY B, 120, 26, 6358-6367, 2016
Synthesis and Thermal Responses of Polygonal Poly(ethylene glycol) Analogues
Shunichi Kawasaki, Takahiro Muraoka, Tsutomu Hamada, Kazuki Shigyou, Fumi Nagatsugi, Kazushi Kinbara
CHEMISTRY-AN ASIAN JOURNAL, 11, 7, 1028-1035, 2016
Diffusion of particles adhering to liposomes
Kazuki Shigyou, Ken H. Nagai, Tsutomu Hamada
2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015, -, 2016
Coupling between pore formation and phase separation in charged lipid membranes
Hiroki Himeno, Hiroaki Ito, Yuji Higuchi, Tsutomu Hamada, Naofumi Shimokawa, Masahiro Takagi
PHYSICAL REVIEW E, 92, 6, 62713-62713, 2015
Shape Effect on Particle-Lipid Bilayer Membrane Association, Cellular Uptake, and Cytotoxicity
Thapakorn Tree-Udom, Jirapom Seemork, Kazuld Shyou, Tsutomu Hamada, Naunpun Sangphech, Tanapat Palaga, Numpon Insin, Porntip Pan-In, Supason Wanichwecharungruang
ACS Applied Materials & Interfaces, 7, 43, 23993-24000, 2015
Molecular behavior of DNA in a cell-sized compartment coated by lipids
Tsutomu Hamada, Rie Fujimoto, Shunsuke F. Shimobayashi, Masatoshi Ichikawa, Masahiro Takagi
PHYSICAL REVIEW E, 91, 6, 62717-62717, 2015
Bringing Macromolecules into Cells and Evading Endosomes by Oxidized Carbon Nanoparticles
Sunatda Arayachukiat, Jiraporn Seemork, Porntip Pan-In, Kittima Amornwachirabodee, Naunpun Sangphech, Titiporn Sansureerungsikul, Kamonluck Sathornsantikun, Chotima Vilaivan, Kazuki Shigyou, Prompong Pienpinijtham, Tirayut Vilaivan, Tanapat Palaga, Wijit Banlunara, Tsutomu Hamada, Supason Wanichwecharungruang
NANO LETTERS, 15, 5, 3370-3376, 2015
Ag/FeCo/Ag Core/Shell/Shell Magnetic Nanoparticles with Plasmonic Imaging Capability
Mari Takahashi, Priyank Mohan, Akiko Nakade, Koichi Higashimine, Derrick Mott, Tsutomu Hamada, Kazuaki Matsumura, Tomohiko Taguchi, Shinya Maenosono
LANGMUIR, 31, 7, 2228-2236, 2015
Self-organization of nanoparticle-membrane systems: Reconstitution of cell migration
Ken H. Nagai, Tsutomu Hamada
Springer Series in Materials Science, 217, 259-270, 2015
Thermodriven Micrometer-Scale Aqueous-Phase Separation of Amphiphilic Oligoethylene Glycol Analogues
Shunichi Kawasaki, Takahiro Muraoka, Haruki Obara, Takerou Ishii, Tsutomu Hamada, Kazushi Kinbara
CHEMISTRY-AN ASIAN JOURNAL, 9, 10, 2778-2788, 2014
Micrometer-Size Vesicle Formation Triggered by UV Light
Tatsuya Shima, Takahiro Muraoka, Tsutomu Hamada, Masamune Morita, Masahiro Takagi, Hajime Fukuoka, Yuichi Inoue, Takashi Sagawa, Akihiko Ishijima, Yuki Omata, Takashi Yamashita, Kazushi Kinbara
Langmuir, 30, 7289-7295, 2014
人工細胞システムの創成と構造制御
濱田勉, 市川正敏
生化学, 86, 2, 209-213, 2014
人工細胞システムの創出に向けた脂質膜インターフェース設計
濱田勉
Colloid and Interface Communication(C&/Commum), 39, 3, 26-27, 2014
Endo- and Exocytic Budding Transformation of Slow-Diffusing Membrane Domains Induced by Alzheimer’s Amyloid Beta
Masamune Morita, Tsutomu Hamada, Mun'delanji C. Vestergaard, Masahiro Takagi
Phys. Chem. Chem. Phys., 16, 19, 8773-8777, 2014
Charge-induced phase separation in lipid membranes
Hiroki Himeno, Naofumi Shimokawa, Shigeyuki Komura, David Andelman, Tsutomu Hamada, Masahiro Takagi
SOFT MATTER, 10, 40, 7959-7967, 2014
ナノ粒子−生体膜相互作用の解析:細胞サイズリポソームを用いた物理化学的アプローチ
濱田勉
BIO INDUSTRY, 30, 6, 48-53, 2013
Dynamic Morphological Changes Induced By GM1 and Protein Interactions on the Surface of Cell-Sized Liposomes
Shruti Dhingra, Masamune Morita, Tsuyoshi Yoda, Mun'delanji C. Vestergaard, Tsutomu Hamada, Masahiro Takagi
MATERIALS, 6, 6, 2522-2533, 2013
Membrane fusion and vesicular transformation induced by Alzheimer's amyloid beta
Mun'delanji C. Vestergaard, Masamune Morita, Tsutomu Hamada, Masahiro Takagi
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1828, 4, 1314-1321, 2013
Antimicrobial activity and mechanism of action of a novel cationic α-helical dodecapeptide, a partial sequence of cyanate lyase from rice
Norihiro Takei, Nobuteru Takahashi, Tomohiro Takayanagi, Atsuo Ikeda, Kenji Hashimoto, Masahiro Takagi, Tsutomu Hamada, Eiichi Saitoh, Akihito Ochiai, Takaaki Tanaka, Masayuki Taniguchi
Peptides, 42, 55-62, 2013
The effect of oxysterols on the interaction of Alzheimer's amyloid beta with model membranes
Huong T.T. Phan, Takahiro Hata, Masamune Morita, Tsuyoshi Yoda, Tsutomu Hamada, Mun'Delanji C. Vestergaard, Masahiro Takagi
Biochimica et Biophysica Acta - Biomembranes, 1828, 11, 2487-2495, 2013
Dynamical formation of lipid bilayer vesicles from lipid-coated droplets across a planar monolayer at an oil/water interface
Hiroaki Ito, Toru Yamanaka, Shou Kato, Tsutomu Hamada, Masahiro Takagi, Masatoshi Ichikawa, Kenichi Yoshikawa
SOFT MATTER, 9, 40, 9539-9547, 2013
Ion permeation by a folded multiblock amphiphilic oligomer achieved by hierarchical construction of self-assembled nanopores
Takahiro Muraoka, Tatsuya Shima, Tsutomu Hamada, Masamune Morita, Masahiro Takagi, Kazuhito V. Tabata, Hiroyuki Noji, Kazushi Kinbara
Journal of the American Chemical Society, 134, 48, 19788-19794, 2012
Thermo-induced Vesicular Dynamics of Membranes Containing Cholesterol Derivatives
Tsuyoshi Yoda, Mun'delanji C. Vestergaard, Tsutomu Hamada, Phuc Thi Minh Le, Masahiro Takagi
LIPIDS, 47, 8, 813-820, 2012
Size-Dependent Partitioning of Nano/Microparticles Mediated by Membrane Lateral Heterogeneity
Tsutomu Hamada, Masamune Morita, Makiyo Miyakawa, Ryoko Sugimoto, Ai Hatanaka, Mun'delanji C. Vestergaard, Masahiro Takagi
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134, 34, 13990-13996, 2012
Physicochemical Profiling of Surfactant-Induced Membrane Dynamics in a Cell-Sized Liposome
Tsutomu Hamada, Hideyuki Hagihara, Masamune Morita, Mun'delanji C. Vestergaard, Yoshio Tsujino, Masahiro Takagi
JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 3, 3, 430-435, 2012
ジャイアントリポソームを用いた細胞機能解析
濱田勉
薬剤学, 72, 4, 211-214, 2012
Selective localization of Alzheimer's amyloid beta in membrane lateral compartments
Masamune Morita, Tsutomu Hamada, Yuiko Tendo, Takahiro Hata, Mun'delanji C. Vestergaard, Masahiro Takagi
SOFT MATTER, 8, 10, 2816-2819, 2012
The Effect of Oxycholesterols on Thermo-sensitivity of Lipid Vesicles
Mun'delanji C. Vestergaard, Tsuyoshi Yoda, Tsutomu Hamada, Yoko Akazawa-Ogawa, Yasukazu Yoshida, Masahiro Takagi
Biochim. Biophys. Acta, Biomembr., 1808, 2245-2251, 2011
Mimicking multipass transmembrane proteins: synthesis, assembly and folding of alternating amphiphilic multiblock molecules in liposomal membranes
Takahiro Muraoka, Tatsuya Shima, Tsutomu Hamada, Masamune Morita, Masahiro Takagi, Kazushi Kinbara
CHEMICAL COMMUNICATIONS, 47, 1, 194-196, 2011
A possible mechanism of cholesteryl glucoside formation involved in heat shock response in the animal cell membrane
Hisako Akiyama, Tsutomu Hamada, Yasuko Nagatsuka, Susumu Kobayashi, Yoshio Hirabayashi, Kimiko Murakami-Murofushi
Cytologia, 76, 1, 19-25, 2011
Photochemical control of membrane raft organization
Tsutomu Hamada, Ryoko Sugimoto, Takeshi Nagasaki, Masahiro Takagi
SOFT MATTER, 7, 1, 220-224, 2011
Lateral phase separation in tense membranes
Tsutomu Hamada, Yuko Kishimoto, Takeshi Nagasaki, Masahiro Takagi
SOFT MATTER, 7, 19, 9061-9068, 2011
Dynamic Response of a Cholesterol-containing Model Membrane to Oxidative Stress
Tsuyoshi Yoda, Mun'delanji C. Vestergaard, Yoko Akazawa-Ogawa, Yasukazu Yoshida, Tsutomu Hamada, Masahiro Takagi
CHEMISTRY LETTERS, 39, 12, 1273-1274, 2010
Membrane Disk and Sphere: Controllable Mesoscopic Structures for the Capture and Release of a Targeted Object
Tsutomu Hamada, Ryoko Sugimoto, Mun'delanji C. Vestergaard, Takeshi Nagasaki, Masahiro Takagi
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132, 30, 10528-10532, 2010
脂質ベシクルの形状安定性と変形ダイナミクス
濱田勉
月刊機能材料, 30, 7, 50-55, 2010
Cholesterol, lipids, amyloid beta, and Alzheimer's
M. Vestergaard, T. Hamada, M. Morita, M. Takagi
Current Alzheimer Research, 7, 3, 262-270, 2010
Real-time observation of model membrane dynamics induced by Alzheimer's amyloid beta
Masamune Morita, Mun'delanji Vestergaard, Tsutomu Hamada, Masahiro Takagi
BIOPHYSICAL CHEMISTRY, 147, 1-2, 81-86, 2010
Biomimetic Microdroplet Membrane Interface: Detection of the Lateral Localization of Amyloid Beta Peptides
Tsutomu Hamada, Masamune Morita, Yuko Kishimoto, Yuuki Komatsu, Mun'delanji Vestergaard, Masahiro Takagi
JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 1, 1, 170-173, 2010
Rhythmic pore dynamics in a shrinking lipid vesicle
Tsutomu Hamada, Yuichi Hirabayashi, Takao Ohta, Masahiro Takagi
PHYSICAL REVIEW E, 80, 5, 51921-51921, 2009
Dynamic Behavior of Giant Liposomes at Desired Osmotic Pressures
Masae Ohno, Tsutomu Hamada, Kingo Takiguchi, Michio Homma
LANGMUIR, 25, 19, 11680-11685, 2009
The conjugation of diphtheria toxin T domain to poly(ethylenimine) based vectors for enhanced endosomal escape during gene transfection
Shinji Kakimoto, Tsutomu Hamada, Yuuki Komatsu, Masahiro Takagi, Toshizumi Tanabe, Hideki Azuma, Seiji Shinkai, Takeshi Nagasaki
BIOMATERIALS, 30, 3, 402-408, 2009
Reversible Control of Exo- and Endo-Budding Transitions in a Photosensitive Lipid Membrane
Ken-ichi Ishii, Tsutomu Hamada, Masaomi Hatakeyama, Ryoko Sugimoto, Takeshi Nagasaki, Masahiro Takagi
CHEMBIOCHEM, 10, 2, 251-256, 2009
細胞サイズリポソームの新しい作成法とその応用
山田彩子, 濱田勉, 吉川研一
生物物理, 49, 256-259, 2009
Artificial-cellular computing
Shin-ichiro M. Nomura, Tsutomu Hamada
Int. J. Unconv. Comput., 5, 87-102, 2009
CONSTRUCTION OF ASYMMETRIC CELL-SIZED LIPID VESICLES FROM LIPID-COATED WATER-IN-OIL MICRODROPLETS
Masahiro Takagi, Tsutomu Hamada, Mun'delanji Vestergaard
IFPT'6: PROGRESS ON POST-GENOME TECHNOLOGIES, PROCEEDINGS, 31-35, 2009
Detection of Alzheimer’s amyloid beta aggregation by capturing molecular trails of individual assemblies
Mun'delanji Vestergaard, Tsutomu Hamada, Masato Saito, Yoshifumi Yajima, Motonori Kudou, Eiichi Tamiya, Masahiro Takagi
Biochem. Biophys. Res. Commun., 377, 2, 725-728, 2008
Construction of Asymmetric Cell-Sized Lipid Vesicles from Lipid-Coated Water-in-Oil Microdroplets
Tsutomu Hamada, Yoko Miura, Yuuki Komatsu, Yuko Kishimoto, Mun'delanji Vestergaard, Masahiro Takagi
JOURNAL OF PHYSICAL CHEMISTRY B, 112, 47, 14678-14681, 2008
Effect of phospholipids on conformational structure of bovine pancreatic trypsin inhibitor (BPTI) and its thermolabile mutants
Naoshige Izumikawa, Shingo Nishikori, Mun'delanji Vestergaard, Tsutomu Hamada, Yoshihisa Hagihara, Noboru Yumoto, Kentaro Shiraki, Masahiro Takagi
BIOPOLYMERS, 89, 10, 873-880, 2008
Using model membranes for the study of amyloid Beta : Lipid interactions and neurotoxicity
Mun'delanji Vestergaard, Tsutomu Hamada, Masahiro Takagi
BIOTECHNOLOGY AND BIOENGINEERING, 99, 4, 753-763, 2008
巨大リポソームの顕微鏡直接観察
濱田勉
生命科学研究レター, 28, 27-31, 2008
Dynamic Processes in Endocytic Transformation of a Raft-Exhibiting Giant Liposome
Tsutomu Hamada, Yoko Miura, Ken-ichi Ishii, Sumiko Araki, Kenichi Yoshikawa, Mun’delanji Vestergaard, Masahiro Takagi
J. Phys. Chem. B, 111, 10853-10857, 2007
Manipulation of cell-sized phospholipid-coated microdroplets and their use as biochemical microreactors
M. Hase, A. Yamada, T. Hamada, D. Baigl, K. Yoshikawa
LANGMUIR, 23, 2, 348-352, 2007
生体モデル膜ラフトドメインの動的構造
濱田勉, 高木昌宏
化学と生物, 45, 6, 436-438, 2007
Spontaneous transfer of phospholipid-coated oil-in-oil and water-in-oil micro-droplets through an oil/water interface
Ayako Yamada, Toru Yamanaka, Tsutomu Hamada, Masahiko Hase, Kenichi Yoshikawa, Damien Baigl
LANGMUIR, 22, 24, 9824-9828, 2006
Transport of a cell-sized phospholipid micro-container across water/oil interface
Masahiko Hase, Ayako Yamada, Tsutomu Hamada, Kenichi Yoshikawa
CHEMICAL PHYSICS LETTERS, 426, 4-6, 441-444, 2006
Domain-growth kinetics in a cell-sized liposome
D Saeki, T Hamada, K Yoshikawa
JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 75, 1, 13602-13602, 2006
Reversible photoswitching in a cell-sized vesicle
T Hamada, YT Sato, K Yoshikawa, T Nagasaki
LANGMUIR, 21, 17, 7626-7628, 2005
Folding transition into a loosely collapsed state in plasmid DNA as revealed by single-molecule observation
YT Sato, T Hamada, K Kubo, A Yamada, T Kishida, O Mazda, K Yoshikawa
FEBS LETTERS, 579, 14, 3095-3099, 2005
Self-running droplet: Emergence of regular motion from nonequilibrium noise
Y Sumino, N Magome, T Hamada, K Yoshikawa
PHYSICAL REVIEW LETTERS, 94, 6, 68301-68301, 2005
気になった論文
濱田勉
生命科学研究レター, 18, 25-27, 2005
Peeling kinetics of giant multilamellar vesicles on a solid-liquid interface
T Hamada, K Yoshikawa
CHEMICAL PHYSICS LETTERS, 396, 4-6, 303-307, 2004
Gene expression within cell-sized lipid vesicles
S Nomura, K Tsumoto, T Hamada, K Akiyoshi, Y Nakatani, K Yoshikawa
CHEMBIOCHEM, 4, 11, 1172-1175, 2003
Cell-Sized Liposomes and Droplets: Real-World Modeling of Living Cells
Tsutomu Hamada, Kenichi Yoshikawa
Materials, 5, 2292-2305,